Benadryl For 80 Pound Dog

Benadryl is safe for dogs, but dont give any to your dog without consulting a vet first as the wrong dose could be toxic.

Your vet may recommend Benadryl to help treat your dog for conditions like hives or anxiety and can guide you on delivering the correct dosage and medication.

Heres what you need to know about how much Benadryl your dog should take and when you need to see the vet.

Benadryl Tablets

According to the Merck Veterinary Manual, the standard dose for Benadryl is 2-4 milligrams per kilogram of body weight, or 0.9-1.8 milligrams (mg) of Benadryl per pound. Therefore, a simple and practical dose is 1 mg of Benadryl per pound of your dog’s weight, given 2-3 times a day.

How long does it take for Benadryl to work in dogs?

It usually takes 24 hours for Benadryl to wear off and stop working. However, for dogs with liver or kidney disease, the effects can last longer. Always talk to your veterinarian before giving Benadryl, especially if your dog has chronic liver, kidney, or heart problems.

What is Benadryl used for in dogs?

Benadryl is a kind of an antihistamine drug. This kind of medication is widely used against any type of allergy. It usually works short-term.

Histamine itself is a substance released by the cells called Mast cells, which triggers our organisms allergy reactions. Moreover, histamine plays a vital role in human brain – thats why its also used to treat motion sickness.

Antihistamine for dogs has multiple applications – our Benadryl dosage for dogs calculator can be used for all of them.

  • Benadryl for anxiety Vets recommend Benadryl for dogs with severe anxiety connected to thunderstorms, traveling, or fireworks.
  • …for allergies Used for mosquito, insects or snake bites, skin, food, or airborne allergies.
  • …for motion sickness Caused by planes, cars, or boats.
  • …for tumor treatment
  • …for heartworm therapy The use of antihistaminic drugs protects your dog from the overreaction of their immune system caused by the heartworm elimination.
  • A list of Benadryl generic drugs of possible allergy pills for dogs, available on the US market:

    Dont give your dog any drugs without medical advice – always consult your veterinarian first!

  • Benadryl
  • Unisom
  • Sominex
  • Genahist
  • ZzzQuil
  • Nytol
  • Quenalin
  • Curious about other drugs for dogs? Check out the following links:

    Can you give a dog Benadryl?

    The answer is both yes and no – always consult your veterinarian first!

    We all know that our regular food might be dangerous to our dogs – lets think about chocolate or grapes. The same goes for human medicine, as it can be pretty harmful to our pets in most situations.

    Whats important to check?

    Lets study the example of Benadryl (or any other diphenhydramine for dogs).

  • Make sure that your tablets/syrup contains only the active substance you want to give to your dog – pay attention to any additional content that is often present in human drugs.
  • Double check if youre giving your dog the right dose! Dont follow advice for humans printed on the medications boxes. Alway use your dogs current weight. Its especially important when you need to find liquid Benadryl dosage for dogs – carefully scan the label for the concentration of the drug, usually given in mg/mL.
  • ‍⚕️ Always consult your veterinarian to ensure that your dogs symptoms are not indicative of a serious disease or illness. Better to be safe than sorry!
  • Get to know your dogs health conditions that might pose a greater risk to its life/health when combined with Benadryl. If your dog has any of the following diseases/states, it shouldnt take Benadryl:
    • Pregnancy
    • Low blood pressure
    • Any severe cardiovascular disease
    • Glaucoma
  • ☎️ Look out for all the adverse effects of Benadryl, and if they occur, consult your vet and/or set aside the medicine. If the adverse effects get severe – act quickly and call for help!
    • Lethargy
    • Dry mouth
    • Urinary retention
    • Vomiting
    • Diarrhea
    • Lack of appetite
  • Weve equipped you with all the essential, practical knowledge about the Benadryl dosage for dogs by weight and its possible effects; time to discover our other dog tools and learn something new!


    How much Benadryl can an 80 pound dog have?

    Benadryl dosage for dogs.

    According to the Merck Veterinary Manual, the safe dosage is 2-4 milligrams of medication per kilogram of weight, or 0.9 to 1.8 milligrams per pound. This amount can be administered two to three times daily, depending on your dog’s symptoms.

    How many 25mg Benadryl can I give my 80 pound dog?


    The general dose of Benadryl (diphenhydramine) is 2 to 4 mg/kg up to three times day. If your dog weighs 25 lbs (11.3 kg) the dose of Benadryl would be 22.6mg to 45.2mg up to three times a day. Benadryl tablets are available in 25mg and 50mg strength.

    Will 25 mg of Benadryl make my dog sleepy?

    The side effects of Benadryl in dogs are similar to the side effects humans might experience with the drug. These include sleepiness, dry mouth, sluggishness, or urinary retention.

    How much human Benadryl can I give my dog?

    The Merck Veterinary Manual recommends administering 2-4 milligrams of Benadryl per kilogram of body weight, two to three times a day.