What To Do?
As seen, inbreeding leads to significant problems because you are dealing with a high concentration of the same genetic material being passed to the offspring. The risks at stake may be too high.
If you are seriously considering inbreeding, consult with a knowledgeable breeder who is willing to be your mentor. Generally, before considering this practice, you should carefully look back into at least three or more generations and determine whether there is any history of health problems or undesirable traits.
Inbreeding should therefore only be done if the breeder can ascertain that both dogs are entirely really healthy, are perfect (or close to perfect examples( of the breed, and have no history of carrying recessive (hidden) traits across several generations. Only then, can inbreeding be considered, keeping in mind though that even in their experts hands, there may risks at stake.
If you do not have any mentor, but are determined to breed, it might be therefore safer to breed two healthy, yet unrelated dogs rather than potentially creating litters of puppies with breed faults, weakened immune and a host of other potential health problems.
Can you breed 2 dogs from the same parents but different litters?
Yes, you can, but it is not recommended. Technically, when you breed dogs from the same parents but different litters, to put it bluntly, you are literally breeding brothers and sisters. … However, there is also risk that negative characteristics from hidden recessive genes may pop up leading to smaller litter size.