Can too much vitamin D cause seizures in dogs? Expert Advice

On this page:

Dogs that eat pet food containing too much vitamin D can develop vitamin D toxicity. It can also occur if a dog accidentally gets into vitamin D supplements that a person in the household is taking. Another common way that dogs get vitamin D toxicity is after accidentally eating certain chemicals meant to kill rodents like rats and mice, called cholecalciferol rodenticides. Cholecalciferol is the chemical name for vitamin D3.

Dogs with excess vitamin D may vomit, have little appetite, drink and urinate more, drool excessively, and/or lose weight. Depending on the concentration of the vitamin D in the food, diet-related toxicity tends to develop more gradually over time. Cases of vitamin D rodenticide or supplement poisoning are rapid onset – showing signs of illness in a matter of hours or days.

If you suspect your dog is showing signs of vitamin D toxicity, take him or her to a veterinarian immediately.

Only a veterinarian can diagnose vitamin D toxicity. He or she will evaluate your dog’s signs, ask about what food the dog is eating and what the dog might have gotten into, and might take a blood sample to measure levels of calcium, phosphorus, and vitamin D or obtain urine to assess kidney function. Depending on the results of a veterinarian’s examination, he or she will determine the best course of action.

Treatment will depend on a veterinarian’s assessment of each case, but the aim will be to remove the source of vitamin D to prevent additional exposure (e.g., stop the feeding of recalled dog food) and to flush the body of the excess vitamin D. In less acute cases of vitamin D toxicity that are caught early, the veterinarian may determine that a change of diet may help resolve the issue within weeks to months, or he or she may choose to prescribe medication. A veterinarian may also continue to monitor blood calcium and phosphorus levels until they return to a healthy baseline.

If your dog is showing signs of vitamin D toxicity such as vomiting, loss of appetite, increased thirst and urination, excessive drooling and/or weight loss, contact a veterinarian immediately. Provide a full diet history to your veterinarian, including what food you (or other household members) give him and also other food or items he might have gotten into. You may find it helpful to take a picture of the pet food label, including the lot number. If your veterinarian suspects the food is the source of excess vitamin D, having the lot code helps the FDA identify exactly when the contamination occurred and what other products might also be affected. For tips about locating and saving pet food lot code information, see: Save Your Pet Food Lot Number! This can help prevent other dogs from getting sick. Don’t feed the products to your pets or any other animals.

Dog owners can report suspected illness to the FDA electronically through the Safety Reporting Portal or by calling your state’s FDA Consumer Complaint Coordinators. It’s most helpful if you work with your veterinarian to submit a dog’s medical records as part of the report. For an explanation of the information and level of detail that would be helpful to include in a complaint to the FDA, please see How to Report a Pet Food Complaint.

It’s also helpful if you save the food in its original package, in case it’s needed for testing. If testing is not needed, contact the company listed on the package for further instructions or throw the products away in a way that children, pets and wildlife cannot access them.

The FDA encourages veterinarians treating vitamin D toxicity related to diet to ask clients for a detailed diet history. We also remind clinicians that vitamin D toxicity may present as hypercalcemia, hyperphosphatemia, and/or renal failure. If you suspect that the pet food is the source of the excess vitamin D, we welcome case reports, especially those confirmed through diagnostics. We ask that you not tell the pet owner to discard the leftover food, but instead to retain it in a safe place and not feed it to their pet or any other animal.

Reports to the FDA can be submitted through the Safety Reporting Portal or by calling your local FDA Consumer Complaint Coordinators. For submissions through the Safety Reporting Portal, when asked “Who are you?” please select, “A private citizen/business submitting a voluntary report,” on the selection screen in order to guide you through a veterinary submission. For an explanation of the information and level of detail that would be helpful to include in a complaint to the FDA, see How to Report a Pet Food Complaint.

What is vitamin D poisoning?

Vitamin D is necessary for the body to absorb calcium, a mineral that is essential for healthy bones, muscle movement, nervous system function, and immune system function. Excessive amounts of Vitamin D may result in poisoning. There are two forms of vitamin D. Plants, fungi, and yeasts produce Vitamin D2 (ergocalciferol) and Vitamin D3 (cholecalciferol) is produced by animals.

Poisoning commonly occurs when pets ingest rodenticides (rat and mouse poisons) containing cholecalciferol or supplements containing either form of Vitamin D. Vitamin D2 (ergocalciferol) has a much wider margin of safety than vitamin D3 (cholecalciferol) and larger amounts are generally more tolerated by animals. Many topical psoriasis medications also contain potent amounts of vitamin D (i.e., calcipotriene, tacalcitol, or calcitriol) and poisoning can occur when pets lick the cream off someone’s skin or directly from the tube of product. Improperly formulated pet foods, both commercially produced and homemade, have also resulted in poisoning.

Getting Into Vitamin D Supplements

Some dogs like to get into anything and everything they can find. When a dog finds Vitamin D supplements, they are usually human supplements that the owner accidentally left within reach. If your dog gets into your medications and eats your Vitamin D supplements, he can easily get enough to cause toxicosis.

Vitamin D Toxicity (Hypervitaminosis D) | Causes, Pathophysiology, Symptoms, Diagnosis, Treatment

Vitamin D is an essential nutrient for most animals, including humans and dogs. While humans and certain animals are able to synthesize Vitamin D from the sun via their skin, dogs mainly get Vitamin D from their diets. Although dogs need Vitamin D to survive and thrive, too much Vitamin D can be toxic to dogs.