Is shaking a symptom of Cushing’s in dogs? A Step-by-Step Guide

How to comfort a dog with Cushing’s disease

What can you do to help your beloved dog? In addition to treating your dog’s Cushing’s disease, here are more things you can do to be vigilant in managing your dog’s condition.

Is shaking a symptom of Cushing’s in dogs?

  • Always have fresh water available. As I mentioned, Cushing’s causes increased thirst and urination, so your dog will want to drink more and need to go out frequently for potty breaks. Make sure you refill the water bowl and giving your dog plenty of opportunities to go potty.
  • Keep a sharp eye on your dog’s skin. If you notice signs of skin infection such as bumps, crusts, hair loss, or red irritated skin, speak with your vet. It is important that skin infections are addressed promptly. In some cases, your vet may also prescribe antifungal and antibacterial shampoos and wipes to proactively help combat skin infections.
  • Watch for signs of urinary issues such as increased frequency of urination, foul odor to the urine, straining to urinate, and/or blood in the urine. If you observe any of these signs, take your dog to your veterinarian. For dogs with Cushing’s, urinary tract infections are nearly impossible to prevent. However, you can help your dog by seeking treatment promptly.
  • Keep in close contact with your veterinarian about any changes in your dog’s symptoms. If you notice vomiting, diarrhea, lethargy in dogs, tremors, or loss of appetite, contact your veterinarian immediately. These may be signs that your dog has flipped from Cushing’s disease (too much cortisol) to Addison’s disease (too little cortisol). Addison’s disease can be life threatening, so it is critical your dog gets veterinary attention right away.
  • Symptoms of Cushing’s Disease in Dogs

    Many people mistake the signs of Cushing’s disease for those of old age.

    The dog gradually slows down, is less energetic and sleeps more.

    Other common symptoms include:

  • Weight gain
  • Sagging stomach that takes on a potbellied appearance
  • Dull and sparse coat
  • Thin skin with blackheads
  • Increased thirst, which increases water intake, resulting in possible lapses in toilet training
  • Another unfortunate consequence of Cushing’s is a high proportion of dogs developing high blood pressure. This makes an unexpected vascular incident, such as a stroke, more likely.

    Indeed, experts in the field believe the high blood pressure associated with Cushing’s disease is the biggest single cause of sudden, unexplained death in older animals.

    This video shows “Peggy dog,” a dog whose shaking is a result of Cushing’s disease:

    What do you feed a dog with Cushing’s disease?

    Your dog should be fed a complete diet as recommended by a veterinary surgeon. Ideally the diet should be low in fat, contain moderate fibre, low salt and highly digestible protein. The diet may need to be tailored to the individual dogs needs.

    Dog Cushings Disease. Dr. Dan covers symptoms, diagnosis, and treatment of Cushing’s disease

    This year my old pooch became fearful, aggressive, crippled and weak, pot-bellied, and incontinent, and started liking sweets. The vets all agreed he was just getting old. I didn’t think so. Here is our story:

    About a year ago, Jim the hound dog had an almost overnight quality-of-life change. He awoke one night in abject terror, whining and shaking with tremors whenever you’d touch him, especially on the head. He didn’t want to sleep alone. That same week he started having trouble with weakness in his hind legs. He had recently started begging to share my pancakes, which was unusual for my normally picky carnivore. Having lost my dogs Max and Kobie to brain tumors, I was certain I was seeing telltale signs of the same awful disease. In a panic, I packed him up and drove him to the vet school for an MRI and was surprised to learn that Jim had a very healthy noggin.

    Later that month, my laid-back hound dog became a scaredy-dog. New people and new dogs were especially scary. He’d charge in fear if they came into his yard, couldn’t regain his composure for hours, and on two occasions, he tried to gum his victim into submission (Jim is challenged in the tooth department). This was such a dramatic change, I felt strongly that it wasn’t a natural aging process. Kim’s dog Kona

    After lots of testing, the veterinarians were in consensus that he had some mild neurological issues but the rest was probably just old age. While all this was happening, Kim Saunders, Petfinder’s first employee, was struggling with a mysterious ailment afflicting her senior pooch, Kona. Through persistence, independent research and the help of a long-distance, invaluable veterinarian friend, she miraculously learned about ATYPICAL Cushing’s disease — basically, Cushing’s disease that doesn’t follow the rules. Cushing’s, which can cause appetite shifts, mood changes, muscle wasting, and more, had been ruled out in both Kona’s and Jim’s cases because their cortisol levels were normal. Cortisol is one of many metabolic hormones that can go awry when there is an issue with the adrenal gland, but it is the commonly accepted marker for diagnosing Cushing’s.

    Despite Kona’s own vet’s assurances that this “could not be Cushings,” Kim insisted on having Kona tested for atypical Cushing’s. Once the diagnosis was confirmed, she put him on a regimen of melatonin and flax lignans as well as a more powerful drug that impairs adrenal function.

    Meanwhile, I was dealing with an increasingly aggressive senior dog and feeling as if the vets had given up on us. On the eve of a family reunion in which I was going to have about 30 people staying with us, I was at my wits’ end. I will never forget being on the phone with Kim and having the realization that many of the symptoms our dogs were having were similar.

    With this new information (and fueled by the fear of Jim gumming my old aunt to a nub), I made a beeline for our local health-food co-op and placed Jim on the holistic-diet portion of the atypical Cushing’s treatment (after verifying that it was safe to do so without a formal diagnosis). Within just two days of melatonin and flax lignans, Jim’s personality calmed and we had a lovely reunion, with my aunts and uncles safely enjoying Jim’s (relative) normalcy.

    Later that month, blood work sent to the lab at the University of Tennessee confirmed that Jim did, indeed, have atypical Cushing’s. His cortisol levels were normal but all the other hormones were way out of whack. Vindicated!

    However, a few months ago, it became clear that Jim’s fearfulness had returned and his muscles were weakening. Once again, he was afraid to walk at night, other dogs were terrifying to him, and he’d expanded the territory he thought he needed to protect. We clearly weren’t managing his Cushing’s anymore. So back to my local vet school I went, where they told me they didn’t really think Jim’s issues were consistent with Cushing’s disease because his cortisol levels were fine. UGH!

    As luck would have it, Jim’s symptoms had progressed to the point that he was having massive panic attacks when he went to the vet (his blood pressure would spike, his hair would fall out, etc.). On this visit, it was so bad that when Jim saw the doctor coming, his tongue turned blue, his stomach distended, and he stopped being able to breath. Convinced that this couldn’t be a panic attack (more common in cats at the vet, not dogs), they were worried about bloat. So they rushed to do an ultrasound of his belly and — voila! — what should they find but a tumor on his adrenal gland — which had finally grown large enough to detect. Thank goodness for Jim’s panic attack. Adrenal tumors can cause unregulated surges of epinephrine — the chemical that produces the fight-or-flight response. It is a very scary experience and explains so much of Jim’s behavior over the last year. Also, atypical Cushing’s disease appears to be commonly associated with adrenal tumors.

    We are now three weeks post surgery (adrenalectomy) in which they found Jim’s tumor was functional and malignant. His symptoms have all but subsided (with the exception of his muscular weakness, which, if reversible, will take some time). He’s back to being a picky carnivore, he enjoys visitors, fancies moonlight walks with his momma again, and is becoming quite svelte as his pot belly shrinks before my eyes.

    Kim lost sweet Kona at 14 years old. Who knows how his disease would have progressed if we had known more about atypical Cushing’s? What are the odds that two senior dogs of two dear friends would have this disease — a disease that is still, for the most part, unaccepted. How many dogs diagnosed with old age have a very treatable form of atypical Cushing’s disease?

    Jim’s surgery cost about $4,000, but I have pet insurance that covers most of it. He’s happily down to a normal amount of daily pills (the Cushing’s pills counted about 20 a day). We’ve opted not to do chemotherapy as a follow up because there appear to be no more tumors, and he’s an old guy who’s already been through chemo once (four years ago).

    I’m relieved that Jim is feeling like Jim, but I remain unsettled that it was so hard to find a vet who would test for this. The fact that it took an accidental conversation to discover the syndrome and an accidental ultrasound to discover the underlying cause makes it worse. My experience, because of Kim’s research, was relatively easy, but what are the odds that a pet parent who isn’t entrenched in the companion-animal industry (or who doesn’t have Kim at her side) would have ever found the treatment or the tumor? I write this because I hope it will promote more testing through the University of Tennessee by vets around the country (thank you, Dr. Oliver, for your lab’s work on this crazy disease).

    Here is a good article about atypical Cushing’s disease — but it is fairly technical. There is very little about it published in layman’s terms. Kim was able to find additional information from the Yahoo group CanineCushings-AutoimmuneCare.